Prof Dr Irinel Popescu

Prof. Dr. Irinel POPESCU

Prof. Dr. Irinel POPESCU MD, PhD, is the Head of “Center of Digestive Diseases and Liver Transplantation Fundeni Hospital, Bucharest and Professor of Surgery at “Titu Maiorescu” University, Faculty of Medicine.

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National and international scientific societies:

Romanian Society of Surgery: President 2006-2008;

Romanian Association of Transplantation (Romtransplant): President 1998- 2018;

Romanian Society of Endoscopic Surgery and other surgical techniques (ARCE): President 2002-2006;

Romanian Association of Hepato‐Biliary‐Pancreatic Surgery and Liver Transplantation: President 2006 – 2017;

European Surgical Association (ESA): Member (2007), President 2018-2019;

European Board of Surgery- Transplant Division (2009) and Hepato-Bilio-Pancreatic Surgery Division (2013);

European Society of Organ Transplantation (ESOT): Member;

International Association of Surgeons and Gastroenterologists (IASG): Member of Executive Committee (2002); Vice President- since 2016;

American College of Surgeons (FACS): Fellow (2005);

Romanian Academy of Medical Sciences Bucharest (Romania): Member (1999), President 2011-Present;

Romanian Academy: Corresponding Member (2013);

Federation of European Academies of Medicine (FEAM): Vice-president 2014- 2017;

Académie Nationale de Médecine France: Membre correspondant étranger ( 2013);

Académie Nationale de Chirurgie (France): Associe étranger (2003).

Editorial activities: Member of Editorial Board

  • Hepatogastroenterology: Editor-in-chief (2011-2012), Senior Honorary Editor ( 2013);
  • Chirurgia (Buc) (The Romanian Journal of Surgery): Editor-in-Chief (2004-2013);
  • Langenbeck’s Archives of Surgery: Associate Editor;
  • Journal of Gastrointestinal and Liver Disease: Member of the Editorial Board;
  • Surgery, Gastroenterology and Oncology: Vice-Editor in Chief.

Visiting Professor

  • Karolinska University in Stockholm (2010);
  • University of Belgrade, School of Medicine (2018).

Visiting Speaker

  • Grand Rounds AKH Vienna, “The surgical treatment of the metastatic colo-rectal cancer” (2015);
  • Universitätsklinikum Hamburg-Eppendorf- “Central pancreatectomy” (2015);
  • Weekly Surgical and Gastroenterological Grand Rounds- Borel-Staehelin-Lecture “How to increase the number of donors in a liver transplant program” – University of Zürich (2014).

Key Note Speaker

  • European Congress of Coloproctology: BJS lecture-“Metastatic CRC – what about the primary?” Vienna (2012).
Prof Dr Irinel Popescu


Kyoichi TAKAORI, M.D., Ph.D., F.A.C.S., Secretary General, IASGO Head, Pancreas Cancer Unit Kyoto University Hospital, is a pancreatic surgeon who has extensive experiences of open, laparoscopic, and robotic surgery.

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His academic career includes Professor of Surgery at Asahi University and Assistant Professor of Physiology and Biophysics at University of Arkansas for Medical Sciences.

Thorough his career as a surgeon, he has struggled to improve the prognosis of pancreatic cancer, which is known as the worst malignancy. First, he has focused on early detection of pancreatic cancer so that surgeons can offer truly curative operations to the patients. In 2003, with Dr. Ralph Hruban, Dr. Takaori organized International Expert Meeting on Precursor Lesions of Pancreatic Cancer and created international consensus on the classification of pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN). World Health Organization has adopted this classification system, which helps investigators better understand the precursor lesions.

Furthermore, in pursuit of early diagnosis and treatment of pancreatic cancer in high-risk individuals, he has founded a Japanese Familial Pancreatic Cancer Registry and is promoting collateral studies as the chairman of the registry committee of Japan Pancreas Society. Second, he has endeavored to improve the surgical techniques for pancreatic malignancies. In order to improve local control and to perform more oncologic resections, he has refined artery-first pancreatoduodenectomy and developed new techniques of artery-first distal pancreatectomy, and artery-first DP-CAR by utilizing the “Tiger’s Den” approach in all open, laparoscopic and robotic surgery.

Third, he is a great believer of multi-disciplinary approach and presently directing the multi-disciplinary team as the Head of Pancreatic Cancer Unit at Kyoto University Hospital. Recently, he has conducted international collaborative study on the clinical managements of pancreatic cancer.

Last but not least, Dr. Takaori has served patient’s activities on the Medical Advisory Board for PanCAN Japan and the Scientific Advisory Board for Pancreatic Cancer UK.

He is Founding Editor of Surgery, Gastroenterology and Oncology, the official journal of the International Association of Surgeons, Gastroenterologists and Oncologists (IASGO), and has served Pancreatology also as the Vice Editor-in-Chief of Pancreatology for over eight years.

Along with Prof. Dan Duda, Prof. Takaori is organizing IASGO World Congresses as well as many Postgraduate Courses for the purpose of “Globalization of Medical Knowledge” all over the world.

Prof Dan G. DUDA


Dan G. DUDA, Associate Professor of Tumor Biology & Translational Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Dr. Duda obtained his DMD from the University of Medicine Iaşi, România in 1993, and earned a PhD in Medical Sciences (GI Surgery) from Tohoku University Graduate School of Medicine, Sendai, Japan in 2001. After graduation, he pursued postdoctoral training with Professor Rakesh K. Jain in the Steele Laboratories for Tumor Biology, Department of Radiation Oncology, MGH and Harvard Medical School in Boston. He became a Junior Faculty member (Instructor) in 2004, and then rose through the ranks to Full Investigator at MGH Research Institute in 2016 and Associate Professor of Tumor Biology (Radiation Oncology) at Harvard Medical School in 2012. In 2016, he was appointed as the Director of Translational Research in Gastrointestinal Radiation Oncology at MGH. He has been active internationally and is currently serving as the Secretary General of the IASGO since 2015. He is a member of the AASLD Liver Fibrosis Special Interest Group. He has also been serving as a panel member for multiple scientific expert/grant review meetings worldwide since 2009, including as a permanent member of the US NCI DMP, ACS TBG, and Belgium FWO Med4 sections. He currently serves as the Chair of the FWO Med4 panel.

The research of Dr. Duda’s laboratory focuses on studies of tumor interaction with its microenvironment, with the goal of identifying the cellular and molecular mechanisms of 1) local tumor progression (in liver cancers) and metastatic tumor progression (in other GI cancers), and 2) treatment resistance in advanced cancers. The ultimate goal is to identify and validate targets for combination therapy with radiotherapy and immunotherapy in preclinical studies, and in parallel conduct studies of biomarkers of response in correlative clinical studies.

Dr. Duda has authored over 200 publications so far, of which 121 are original reports. He has been invited to present his results at nearly 200 local, national and international meetings, including Grand Rounds, Plenary Talks and Keynote Lectures. For his work, Dr. Duda received several awards, including from the American Association for Cancer Research, Cancer Research Institute, International Association of Surgeons, Gastroenterologists and Oncologists (IASGO), MGH and the Granara-Skerry Trust for Pancreatic Cancer Research. He is an Honorary Member of the Academy of Medical Sciences of Romania since 2012.

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Prof Luca Aldrighetti


Prof. Luca Aldrighetti, MD, PhD, is Director of the Hepatobiliary and General Surgery Division at San Raffaele Hospital, Milan, Italy. Scientific Director of the Italian Group of Minimally Invasive Liver Surgery (IGoMILS) and Coordinator of the Italian Registry of Laparoscopic Liver Resections.

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Member of the Council and Chair of the Registry Committee of the International Laparoscopic Liver Society (ILLS). Primary clinical and research activities include surgical oncology topics on colorectal liver metastases, perihilar and intrahepatic cholangiocarcinoma and hepatocellular carcinoma, techniques for liver resection (including two stage hepatectomies and ALPPS procedures), and minimally invasive hepatobiliary surgery (including major hepatectomies, resection in postero-superior segments and in cirrhosis), with a personal series of more than 2900 liver resections, more than 1000 of which performed laparoscopically. He has published more than 300 papers, including many studies on techniques, learning curve and outcomes of laparoscopic liver resections. Current H index is 41. He continues with teaching and tutoring activities in a number of national and international courses in both open and laparoscopic liver surgery.

Prof Dr Irinel Popescu

Prof. Dr. Aleksandar R. KARAMARKOVIĆ

Prof. Dr. Aleksandar R. Karamarković, MD, PhD, FACS is Full Professor of Surgery at Faculty of Medicine University of Belgrade and Director, Clinic for Surgery at University Clinical Center “Zvezdara” Belgrade, SERBIA.

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  • M.D. Degree, at University of Belgrade, Medical Faculty, Belgrade / SERBIA (1982-1987), Overall score: 9.93 out of 10.0
  • Ph.D. at University of Belgrade, Medical Faculty, Postgraduate School, Belgrade / SERBIA (1998-2000.)


  • Chief Intensive Care Unit – Department for Surgical Infection and Sepsis Clinic for Emergency Surgery, Clinical Center of Serbia Belgrade / SERBIA (1995-2004)
  • Head Department of HPB Surgery – Clinic for Emergency Surgery, Clinical Center of Serbia Belgrade / SERBIA (2004-2008)
  • Director – Clinic for Emergency Surgery, Clinical Center of Serbia Belgrade / SERBIA (2008-2016)
  • Senior Consultant – HPB Surgery Faculty of Medicine University of Belgrade, Clinical Center of Serbia Belgrade / SERBIA (2016-2018)
  • Director – Clinic for Surgery “Nikola Spasic”, University Clinical Center “Zvezdara” Belgrade / SERBIA (2018-present)


Elected Full Professor of Surgery Faculty of Medicine University of Belgrade / SERBIA (2016-present)


  • International Association of Surgeons, Gastroenterologists & Oncologists (IASGO)
  • Fellow of the American College of Surgeons (FACS)
  • European Surgical Association (ESA) Member
  • World Society of Emergency Surgery (WSES) – National Delegate of Serbia


  • British Journal of Surgery
  • World Journal of Gastroenterology
  • World Journal of Surgical Oncology
  • World Journal of Emergency Surgery
  • World Journal of Hepatology
  • World Journal of Gastrointestinal Oncology
  • Radiology and Oncology
  • Liver Cancer
  • Journal of Investigative Surgery
  • JoVE
  • Digestive surgery


  • Monography: “Intra-abdominal Infections and Septic Syndrome in Abdominal Surgery”, 2002
  • University Book editor: Liver Resections (with operative surgery techniques – CD), 2012
  • Original Articles: 100 covered by (Current Contents (CC); Science Citation Index (SCI); Pub-Med; Medline)


Invited Faculty at more than 60 International and Regional Congresses and Meetings

Prof Ender Dulundu

Prof. Ender DULUNDU

Ender Dulundu is an attending faculty and surgeon in general surgery and HPB Unit in Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Istanbul where he is also the director and founder of the Liver Transplantation Programme.

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Dr. Dulundu focused on surgical treatment of primary and metastatic liver cancer, intraoperative ultrasound examination of the liver, parenchymal sparing of liver surgery, pancreatic cancer, hilar cholangiocarcinoma, oncologic surgery, and liver transplantation

He graduated from University of Istanbul, Cerrahpasa Medical School, and finished residency Haydarpasa Numune Education and Research Hospital, Istanbul. In his last year of residency has visited as a visiting doctor to Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan. And then in 2003 and 2004 He worked as a Fellow of the Japanese Foundation for Promotion of Cancer Research in the same center.

He was a founder of HPB and Liver Transplantation Unit at Haydarpasa Numune Eductaion and Research Hospital, Istanbul in 2006. In 2011 he found and starts successful Liver Transplantation program and chair the HPB Unit in Department of General Surgery, University of Marmara, School of Medicine, Istanbul, and until 2021 worked there as an HPB and Head of the Liver Transplantation Unit.

He has contributed extensively in professional activities in his areas of expertise He served as a president or general secretary to more than 10 international congress and meeting, participate regularly at local and international conferences as an invited speaker, and has published national & international research articles and book chapters.
Prof. Dulundu is Member in Executive Board of Surgery of IASGO (International Associations Surgeons, Gastroenterologists, and Oncologists), A member of Executive Committee and Head of Educational Committee of Turkish HPB Association.

Prof Dr Irinel Popescu

Prof. Marco V. MARINO

Prof. Marco V. Marino, MD PhD FEBS FACS FICS, General surgeon at Istituto Villa Salus, Siracusa, Italy. Medical Director of CAVA Robotics LLC. 

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  • Bachelor Degree 110 cum Laude at the University of Pavia (Italy)
  • Diploma of Specialization in General Surgery 50 cum Laude at the University of Palermo (Italy)
  • Diploma in Laparoscopic Surgery at the University of Strasbourg (France)
  • Diploma in Robotic Surgery at the University of Nancy-Lorraine (France)
  • II Level Master Degree in Robotic Surgery at the University of Pisa (Italy)
  • Fellowship in Robotic Surgery at the Marques de Valdecilla University Hospital of Santander (Spain) in HPB Surgery at the Institute Mutualiste Montsouris of Paris (France) in Upper GI Surgery at Yonsey University of Seoul (South Korea)
  • Ph.D in Oncologic Surgery at the Maria-Slodowska Curie University of Krakow (Poland)
  • Assitant Medical Director of CAVA Robotics LLC. (US)

Titoli e Riconoscimenti:

  • Fellow in HPB of the European Board of Surgeons (FEBS)
  • Fellow of the American College of Surgeons (FACS)
  • Fellow of the International College of Surgeons (FICS)
Prof Dr Irinel Popescu

Prof. Michael LINECKER

Prof. Michael Linecker, University Medical Center Schleswig-Holstein; Campus Kiel; Germany · Department of Surgery and Transplantation MD PhD

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Professional Career

2003 – 2009

2007 – 2009

Medical School
Medical University of Innsbruck, Austria
MD Thesis: Pancreas – Retransplantation: Outcome and risks for graft loss”
University Hospital of Innsbruck, Austria
Clinic for Visceral-, Transplantation- and Thoracic Surgery
Supervisors: Prof. W. Mark, MD; M. Biebl, MD

2009 – 2012

Residency in Surgery
University Hospital of Zurich, Switzerland
Department of Surgery and Transplantation, Prof. P.-A. Clavien, MD, PhD

2012 – 2015

Research Fellowship (MD-PhD Program)
Institute of Molecular Life Sciences, University of Zurich (UZH) and Swiss Federal Institute of Technology (ETH)

PhD Thesis:
Exploring Novel Strategies for Improved Outcomes of Surgery on Fatty Liver“


Intensive Care Unit
University Hospital of Zurich
Intensive Care Unit for Visceral Surgery, Peter Steiger, MD

2016 – 2018

Chief Residency in Surgery
Cantonal Hospital Baden and University Hospital of Zurich
Department of Surgery and Transplantation


Surgical Board Certification of the Swiss Medical Association (FMH), General Surgery

2018 – 2020

HPB and Transplant Fellowship
University Hospital of Zurich, Department of Surgery and Transplantation, Prof. P.-A. Clavien, MD, PhD


Venia legendi (Habilitation) in the field of Surgery, University of Zurich

since 2020

Consultant Surgeon, Liver Surgery and Transplantation
University Medical Center Schleswig-Holstein, Campus Kiel
Department of Surgery and Transplantation, Prof. T. Becker, MD

Clinical Trials

2012 – 2018 A randomized, double-blind study of the effects of omega-3 fatty acids (OmegavenTM) on outcome after major liver resection”
Co-Principle Investigator (Co-PI), Phase III Randomized Controlled Trial, Invesitgator Initiated, Multicentric (Zurich, Bucharest, Moscow)
PI: Prof. P.-A. Clavien, MD, PhD
Clinical ID: NCT01884948
since 2014 International ALPPS registry ALPPSREG (
Registry Coordinator
PI: Prof. P.-A. Clavien, MD, PhD
Clinical ID: NCT01924741

Grants & Sponsorships


Sassella Grant “Associating Liver Partition with Portal vein ligation for Staged hepatectomy (ALPPS) versus Two-Stage Hepatectomy (TSH) for marginally resectable colorectal liver metastases – a multicentric, randomized controlled trial”; CHF 20.000,-


Astellas Travel Grant “Advancing Transplantation Meeting”; Stockholm, Sweden


Swiss Surgical Society (SGC) Sponsorship – Junior Surgeon for the Swiss Surgical Team (SST) Mission Tajikistan 2015


Travel grant, International Congress of the European- African Hepato-Pancreato-Biliary Association (E-AHPBA), 12th Congress, Mainz


Co-Applicant “When is liver transplantation inappropriate?

Considering severity of liver disease and and cancer” Hanne Liebermann-Stiftung, Zurich; CHF 172.233,-

Reviewer Assignments

Annals of Surgery
British Journal of Surgery
Liver Transplantation

Committees / Panel Chair

2017 Session: The Young Surgeon
Chair: Linecker M, Dervenis C
12th International Congress of the European- African Hepato-Pancreato-Biliary Association (E-AHPBA).
23/05/2017 – 26/05/2017, Mainz, Germany
2017 Session: Liver Metastases – Perspectives
Chair: Alikhanov R, Linecker M
Eurasian Federation of Oncology (EAFO) Hepatobiliary Forum
25/06/2017, St. Petersburg, Russia
2018 Session: Management of Intrahepatic Cholangiocarcinoma
Chair: Linecker M, Oldhafer K
13th International Hepato-Pancreato-Biliary Association (IHPBA) Congress.
04/09/2018, Geneva, Switzerland
2021 – 2023 Nomination to the Scientific Programme Committee of the
European- African Hepato-Pancreato-Biliary Association


International Heptato-Pancreato Biliary Association (IHPBA)
European-African Heptato-Pancreato Biliary Association
European Society for Organ Transplantation (ESOT)
Swiss Surgical Society (SGC)
Swiss Association for Laparoscopic and Thoracoscopic Surgery (SALTC)
Austrian Surgical Society (ÖGC)
German Society for Organ Transplantation (DTG)
German Society for Surgery (DGC)
Austrian Society for Alpine and High- Altitude Medicine (ÖGAHM)

Invited lectures

1. Linecker M
New translational insights in ALPPS
117th Annual Congress of the Japan Surgical Society.
27/04/2017– 29/04/2017, Yokohama, Japan.

2. Linecker M
Current studies in ALPPS – What is evidence based?
12th International Congress of the European- African Hepato-Pancreato-Biliary Association (E-AHPBA).
23/05/2017 – 26/05/2017, Mainz, Germany.

3. Linecker M
The evolution of ALPPS: Technical and safety aspects
Eurasian Federation of Oncology (EAFO) Hepatobiliary Forum.
25/06/2017, St. Petersburg, Russia.

4. Linecker M
Report of the International ALPPS Registry
ALPPS Expert Conference.
13th International Hepato-Pancreato-Biliary Association (IHPBA) Congress.
04/09/2018, Geneva, Switzerland.

5. Linecker M
ALPPS – At which stage of development are we?
13th Congress of the European- African Hepato-Pancreato-Biliary Association (E-AHPBA) 2019
06/05/2019, Amsterdam, the Netherlands.

6. Linecker M
Update on ALPPS
Eurasian Federation of Oncology (EAFO) Hepatobiliary Forum.
11/04/2020, Moscow, Russia. (CANCELLED DUE TO COVID-19 PANDEMIC)

7. Linecker M
What are the expectations of the trainees instructors and mentors? – Fellow perspective
ILTS Joint International Congress of ILTS, ELITA & LICAGE
Featured Symposium 6: Maintaining Excellence. 08/05/2021, ILTS Virtual Congress

Prof Dr Irinel Popescu

Gabriel ONISCU

Gabriel C Oniscu, MD, FRCS(Ed), FRCS(Glas) | Consultant Transplant Surgeon | NRS Career Research Clinician | Honorary Reader in Transplantation, graduated from the University of Medicine of Iasi, Romania. He has completed his surgical training in Edinburgh, Birmingham, King’s College Hospital, London and Assan Medical Centre Seoul and obtained a doctorate from the University of Edinburgh.

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Mr. Oniscu is a consultant transplant surgeon at the Royal Infirmary of Edinburgh and Honorary Reader at the University of Edinburgh. He is involved in liver, kidney and pancreas transplantation and is the lead clinician for the living donor kidney transplant programme. He is also the led clinician for novel perfusion and preservation technologies in transplantation in Edinburgh.

He has a strong research activity with particular focus on transplant outcomes, organ perfusion and reconditioning and optical sensing. He is the recipient of the NRS Career Research Fellowship and an MRC confidence in concept award for technological developments relating to normothermic perfusion. Mr. Oniscu is associated with the Liver stem cells and regeneration research group at the Centre for Regenerative Medicine Edinburgh. He is a lead investigator in the NIHR Access to Transplantation and Transplant Outcomes study, the UK NHSBT service evaluation of normothermic regional perfusion in DCD donors and the MRC study investigating the regenerative capacity of liver ductular cells. He has received more than £4.5 mil in research funding.

Mr. Oniscu is Secretary of the European Society for Organ Transplantation and chairs the Research, Innovation and Novel Technologies Advisory Group at NHS Blood and Transplant.

He has authored more than 65 papers and 12 book chapters and is the editor of Abdominal Organ Retrieval and Transplantation Bench Surgery (Wiley) and Springer Atlas of Transplantation Surgery (in press).